The RWD & RWE Podcast

28 June 2023: Conversation with Dan O'Connor, Managing Partner at Contour Ridge – We had an interactive conversation on the RWD/RWE market, trends, and future.

21 June 2023: Conversation with AI entrepreneur, Aaron Leibtag, CEO of Pentavere.ai – We discussed AI based approaches to clinical care and research patient selection, including a great foundation on what NLP is and how it is evolving.

14 June 2023: Conversation with Tom Dougherty MBA, Director of RWE Partnerships & Innovation at Pfizer – We discussed challenges navigating the RWD market space and characteristics of the ideal RWD partner; as well as driving innovation within a large life sciences company.

07 June 2023: Conversation with serial entrepreneurs Keith & Kevin Kallmes (Nested Knowledge, Marblehead Medical, Superior Medical Experts) – We discussed a non-technical, exploratory conversation about the use of AI to establish a unified protocol supporting evidence synthesis in global Health Technology Assessment (HTA) regulatory submissions.

References during the discussion:
- https://www.eunethta.eu/
- https://about.nested-knowledge.com/2023/01/18/can-chatgpt-do-your-next-systematic-review/
- https://www.linkedin.com/posts/nested-knowledge_how-is-nested-knowledge-deploying-ai-today-activity-7055245807561687040-TglG

From the live chat:
[00:21] Madhusudan Kabra: SLR - clinical, economic, utility values etc. in a embase etc.
[00:22] Stu McCully: The requirements of EUnetHTA will be replaced by the EU Health Technology Assessment Regulation in May 2025
[00:22] David Thompson: And it's pronounced yoo-NET-uh
[00:29] Stu McCully: ChatGPT - totally agreement with Kevin’s concerns about its limitations
[00:40] Charlie Barr: Would add “priorities” and “silos” to “urgency” as reasons why the ideal global dossier isn’t always created at the beginning of HTA preparation process
[00:42] Madhusudan Kabra: There are auto- SLR options available - DistllerSR etc. what you are saying Kevin is the next level in this evolution as to what does it make me understand from this data? Is this correct?

24 May 2023: 100th RWW: Conversation with David Thompson PhD, RWE thought-leader – We discussed his reflections on the market for RWD and RWE services, how it is simultaneously crowded and highly fragmented; the influence of regulatory agencies on RWE generation, both pro & con; the confluence of AI and RWE, and how these might combine to radically alter medical decision making at the point of care.

17 May 2023: Conversation with Leanne Larson, MHA, Principal at ZS Associates – We discussed the future of RWE - what will the Inflation Reduction Act (IRA) and FDA guidances on drug development mean for RWE?

10 May 2023: We’re at ISPOR and we discussed interesting things we saw/heard/learned. ISPOR attendees joined the discussion and provided their thoughts/insights

03 May 2023: Conversation with David Lindsay, MD, PhD, CEO of Oncora Medical – We discussed the use of public health real-world data and associated RWE use cases.

26 April 2023: Conversation with Andrea Thoumi MPP MSc and Kamaria Kaalund of the Duke-Margolis Center for Health Policy – We discussed the use of real-world data to inform community-engagement, diversity and inclusiveness across race and ethnicity.

19 April 2023: Conversation with Eirini Schlosser, Founder & CEO at Dyania Health – We discussed large language models (LLMs) — what are they, how are they used, what context is needed, availability, deployment — and the ROI of NLP turn healthcare inefficiencies into redundancies